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Phosphatidylethanolamine, egg

CATALOG # 1045

Specifications

  • Catalog #:1045
  • Scientific Name:Phosphatidylethanolamine, egg
  • Common Name:PE
  • Empirical Formula:C41H78NO8P (oleoyl) Typical fatty acid content
  • CAS#39382-08-6
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:744 (oleoyl)
  • Unit:50 mg/ml, 1ml
  • Solvent:chloroform
  • Source:natural
  • Purity:98+%
  • Analytical Methods:TLC, identity confirmed by MS
  • Natural Source:chicken, egg
  • Solubility:chloroform
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:Yes

Description

Application Notes:

Phosphatidylethanolamine (PE) is frequently the main lipid component of microbial membranes and the second most abundant phospholipid in mammals, comprising as much as 45% of brain lipids. They are concentrated in mitochondria and are key building blocks of membrane bilayers where they are distributed asymmetrically with the majority confined to the inner leaflet. It appears that a primary role for PE, in bacterial membranes at least, is simply to dilute the high negative charge density of the anionic phospholipids. PE acts as a chaperone in transport membrane folding.1 In animals PE is involved in the secretion of very-low-density lipoproteins and aids in membrane fusion and fission.2 In plants lyso PE retards senescence by inhibiting phospholipase D. PE is the precursor to many important lipids. PE acts as a protein transport from the membrane to the vacuole. PE is synthesized through the CDP-ethanolamine or the PS decarboxylation pathway. PE can be converted to diacyl glycerol as a second messenger.3

References:
1. M. Bogdanov, W. Dowhan, Journal of Biological Chemistry, Vol. 274 pp. 36827-36830, 1999
2. J. Vance, Journal of Lipid Research, Vol. 49 pp. 1377-1387, 2008
3. D. Lang et al., Journal of Neurochemistry, Vol. 65 pp. 810, 1995
Price $250.00

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