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Octadecadienoic acid (all cis-9,12)

CATALOG # 1024

Specifications

  • Catalog #:1024
  • Scientific Name:Octadecadienoic acid (all cis-9,12)
  • Common Name:C18:2 (all cis-9,12) Fatty acid; Linoleic acid
  • Empirical Formula:C18H32O2
  • CAS#:60-33-3
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:280
  • Unit:1 gram
  • Solvent:none
  • Source:natural
  • Purity:99%
  • Analytical Methods:GC, TLC
  • Natural Source:plant
  • Solubility:hexane, ethyl ether, ethanol
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No

Description

Application Notes:

Linoleic acid is an 18 carbon, omega-6 fatty acid that is abundant in many plant oils. It is an essential fatty acid in animals and is the precursor in the synthesis of arachidonic acid and other polyunsaturated fatty acids. The conjugated linoleic acids c9,t11 and t10,c12 inhibit linoleic acid elongation to eicosadienoic acid.1 Linoleic acid supplements have been used to try to help prevent cystic fibrosis, dermatitis, and diabetes but the precise mechanisms have proven elusive. It is commonly used in dermatological cosmetics, soaps, and emulsifiers. In some fungus linoleic acid is converted to oxylipins, important compounds of the fungal life cycle,2 and it may play a direct role in the epidermal permeability barrier.3

References:
1. L. Chuang et al. “Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase” Lipids, Vol. 36(10), pp. 1099-1103, 2001
2. M. Wadman et al. “Conversion of linoleic acid into novel oxylipins by the mushroom Agaricus bisporus” Lipids, Vol. 40(11) pp. 1163-1170, 2005
3. P. Elias, B. Brown, V. Ziboh “The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in Barrier Function” Journal of Investigative Dermatology, Vol.74 pp. 230–233, 1980
Price $81.00

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