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Hexadecenoic acid (cis-9)

CATALOG # 1016


  • Catalog #:1016
  • Scientific Name:Hexadecenoic acid (cis-9)
  • Common Name:C16:1 (cis-9) Fatty acid; Palmitoleic acid
  • Empirical Formula:C16H30O2
  • CAS#:373-49-9
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:254
  • Unit:100 mg
  • Solvent:none
  • Source:natural
  • Purity:99%
  • Analytical Methods:GC, TLC
  • Natural Source:plant
  • Solubility:chloroform, hexane, ethyl ether
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No


Application Notes:

Hexadecenoic acid (cis-9) is often found as a component of human adipose tissues, esterified to glycerol and is found in small amounts in most animals. It is synthesized from palmitic acid by the enzyme delta-9-desaturase. Hexadecenoic acid (cis-9) is thought to be biomarker for the de novo synthesis of fatty acids from glucose. It has been reported that there is a consistant positive association between changes in inflammatory markers and hexadecenoic acid (cis-9). Hypercaloric high carbohydrate diets have been shown to stimulate the production of several fatty acids including hexadecenoic acid (cis-9) and its increase is a marker of lipogenesis.1 Hexadecenoic acid (cis-9), because it is a product of stearoyl-CoA desaturase activity, can be used as a biomarker for triglyceridemia and abdominal adiposity.2 It has been demonstrated that oleic and Hexadecenoic acids (cis-9) can inhibit the cytotoxic activity of trans-10, cis-12-conjugated linoleic acid.3 Hexadecenoic acid (cis-9) has been classified as a lipid hormone which stimulates insulin in muscles.4

1. C. Forsythe “Comparison of Low Fat and Low Carbohydrate Dietson Circulating Fatty Acid Composition and Markers of Inflammation” Lipids, Vol. 43 pp. 65-77, 2008
2. F. Paillard et al. “Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity” Nutrition, Metabolism, and Cardiovascular Diseases, Vol. 18(6) pp. 436-440, 2008
3. M. Yamasaki et al. “Alleviation of the cytotoxic activity induced by trans10, cis-12-conjugated linoleic acid in rat hepatoma dRLh-84 cells by oleic or palmitoleic acid” Cancer Letters, Vol. 196(2) pp. 187-196, 2003
4. Z. Yang, H. Miyahara, A. Hatanaka “Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes” Lipids in Health and Disease, vol. 10 pp. 120, 2011
Price $87.00

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