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Hexadecenoic acid (cis-9)

CATALOG # 1016

Specifications

  • Catalog #:1016
  • Scientific Name:Hexadecenoic acid (cis-9)
  • Common Name:C16:1 (cis-9) Fatty acid; Palmitoleic acid
  • Empirical Formula:C16H30O2
  • CAS#:373-49-9
  • SDS:View Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:254
  • Unit:100 mg
  • Solvent:none
  • Source:natural
  • Purity:99%
  • Analytical Methods:GC, TLC
  • Natural Source:plant
  • Solubility:chloroform, hexane, ethyl ether
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No

Description

Application Notes:

Hexadecenoic acid (cis-9) is often found as a component of human adipose tissues, esterified to glycerol and is found in small amounts in most animals. It is synthesized from palmitic acid by the enzyme delta-9-desaturase. Hexadecenoic acid (cis-9) is thought to be biomarker for the de novo synthesis of fatty acids from glucose. It has been reported that there is a consistant positive association between changes in inflammatory markers and hexadecenoic acid (cis-9). Hypercaloric high carbohydrate diets have been shown to stimulate the production of several fatty acids including hexadecenoic acid (cis-9) and its increase is a marker of lipogenesis.1 Hexadecenoic acid (cis-9), because it is a product of stearoyl-CoA desaturase activity, can be used as a biomarker for triglyceridemia and abdominal adiposity.2 It has been demonstrated that oleic and Hexadecenoic acids (cis-9) can inhibit the cytotoxic activity of trans-10, cis-12-conjugated linoleic acid.3 Hexadecenoic acid (cis-9) has been classified as a lipid hormone which stimulates insulin in muscles.4

References:
1. C. Forsythe “Comparison of Low Fat and Low Carbohydrate Dietson Circulating Fatty Acid Composition and Markers of Inflammation” Lipids, Vol. 43 pp. 65-77, 2008
2. F. Paillard et al. “Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity” Nutrition, Metabolism, and Cardiovascular Diseases, Vol. 18(6) pp. 436-440, 2008
3. M. Yamasaki et al. “Alleviation of the cytotoxic activity induced by trans10, cis-12-conjugated linoleic acid in rat hepatoma dRLh-84 cells by oleic or palmitoleic acid” Cancer Letters, Vol. 196(2) pp. 187-196, 2003
4. Z. Yang, H. Miyahara, A. Hatanaka “Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes” Lipids in Health and Disease, vol. 10 pp. 120, 2011
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