9(Z),11(E)-Octadecadienoic acid

CATALOG # 1245
Amount 25 mg
Price $155.00
9(Z),11(E)-Octadecadienoic acid
  • Catalog #:1245
  • Scientific Name:9(Z),11(E)-Octadecadienoic acid
  • Common Name:9-cis, 11-trans CLA
  • Empirical Formula:C18H32O2
  • CAS#2540-56-9
  • SDSView Safety Data Sheet
  • Data Sheet:View Data Sheet
  • Formula Weight:280
  • Unit:25 mg
  • Solvent:none
  • Source:synthetic
  • Purity:98+%
  • Analytical Methods:GC; TLC; identity confirmed by MS
  • Solubility:chloroform, ethanol, hexane, methanol, DMSO
  • Physical Appearance:liquid
  • Storage:-20°C
  • Dry Ice:No
  • Hazardous:No
  • Literature References:Application Notes:

    9(Z),11(E)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. 9(Z),11(E)-Octadecadienoic acid is the major natural isomer of CLA constituting 73% to 93% of the total CLA in dairy products2 and it appears to be the most biologically active isomer. It appears to enhance animal growth and inhibit osteoclast formation and activity from human cells,3 as well as decrease LDL:HDL and total HDL:cholesterol levels in humans.4

    1. Helen B. MacDonald, Journal of the Amer. College of Nutr., Vol 19, No. 90002, 111S-118S, 2000
    2. M. Belury, Annual Review of Nutrition, July Vol.22, 505, 2002
    3. Ilana Platt, Ahmed El-Sohemy, Lipids in Health and Disease, 8:15, 2009
    4. S. Tricon, et al., The American Journal of Clinical Nutrition, 80:614, 2004